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1

Eugenol and isoeugenol as antiproliferative agents in skin cancer cells

Michaela Kalmes, Jennifer Hennen, Brunhilde Blömeke

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 58 KB

english, 2009

2

Metabolism of Δ³-Carene by Human Cytochrome P450 Enzymes: Identification and Characterization of Two New Metabolites

Duisken, Mike, Benz, Dorina, Peiffer, Thomas, Blomeke, Brunhilde, Hollender, Juliane

Journal:

Current Drug Metabolism

Year:

2005

Language:

english

File:

PDF, 200 KB

english, 2005

3

Skin sensitization quantitative risk assessment for occupational exposure of hairdressers to hair dye ingredients

Goebel, Carsten, Diepgen, Thomas L., Blömeke, Brunhilde, Gaspari, Anthony A., Schnuch, Axel, Fuchs, Anne, Schlotmann, Kordula, Krasteva, Maya, Kimber, Ian

Journal:

Regulatory Toxicology and Pharmacology

Year:

2018

Language:

english

File:

PDF, 948 KB

english, 2018

4

Respiratory sensitization: toxicological point of view on the available assays

Chary, Aline, Hennen, Jennifer, Klein, Sebastian G., Serchi, Tommaso, Gutleb, Arno C., Blömeke, Brunhilde

Journal:

Archives of Toxicology

Year:

2018

Language:

english

File:

PDF, 1.24 MB

english, 2018

5

Identification of N-Acetyltransferase 2 Genotypes by Continuous Monitoring of Fluorogenic Hybridization Probes

Brunhilde Blömeke, Sonja Sieben, Dorette Spötter, Olfert Landt, Hans F. Merk

Journal:

Analytical Biochemistry

Year:

1999

Language:

english

File:

PDF, 229 KB

english, 1999

6

MnSOD polymorphisms in sensitized patients with delayed-type hypersensitivity reactions to the chemical allergen para-phenylene diamine: A case–control study

Richard Brans, Heinrich Dickel, Thomas Bruckner, Pieter-Jan Coenraads, Michael Heesen, Hans F. Merk, Brunhilde Blömeke

Journal:

Year:

2005

Language:

english

File:

PDF, 89 KB

english, 2005

7

Impact of para-phenylenediamine on cyclooxygenases expression and prostaglandin formation in human immortalized keratinocytes (HaCaT)

Ruth Moeller, Jutta Lichter, Brunhilde Blömeke

Journal:

Year:

2008

Language:

english

File:

PDF, 970 KB

english, 2008

8

Lack of association between the –260 C→T promoter polymorphism of the endotoxin receptor CD14 gene and the CD14 density of unstimulated human monocytes and soluble CD14 plasma levels

Michael Heesen, Brunhilde Blömeke, Bernhard Schlüter, Nicole Heussen, Rolf Rossaint, Dagmar Kunz

Journal:

Intensive Care Medicine

Year:

2001

Language:

english

File:

PDF, 79 KB

english, 2001

9

Determination of p-phenylenediamine and its metabolites MAPPD and DAPPD in biological samples using HPLC-DAD and amperometric detection

Axel Meyer, Brunhilde Blömeke, Klaus Fischer

Journal:

Journal of Chromatography B

Year:

2009

Language:

english

File:

PDF, 529 KB

english, 2009

10

Cryobanking of viable biomaterials: implementation of new strategies for conservation purposes

DOMINIK LERMEN, BRUNHILDE BLÖMEKE, ROBERT BROWNE, ANN CLARKE, PAUL W. DYCE, THOMAS FIXEMER, GÜNTER R. FUHR, WILLIAM V. HOLT, KATARINA JEWGENOW, RHIANNON E. LLOYD, STEFAN LÖTTERS, MARTIN PAULUS, GORDON

Journal:

Molecular Ecology

Year:

2009

Language:

english

File:

PDF, 73 KB

english, 2009

11

Elicitation response characteristics to mono- and to N,N′-diacetyl-para-phenylenediamine

Brunhilde Blömeke, Tim Pietzsch, Hans F. Merk

Journal:

Contact Dermatitis

Year:

2008

Language:

english

File:

PDF, 83 KB

english, 2008

12

Reactivity of in vitro activated human T lymphocytes to p-phenylenediamine and related substances

Claudia Skazik, Silke Grannemann, Liane Wilbers, Hans F. Merk, Pieter-Jan Coenraads, Sebastian Breuer, Brunhilde Blömeke

Journal:

Contact Dermatitis

Year:

2008

Language:

english

File:

PDF, 412 KB

english, 2008

13

Ascaridole, a sensitizing component of tea tree oil, patch tested at 1% and 5% in two series of patients

Christiaan V Bakker, Brunhilde Blömeke, Pieter-Jan Coenraads, Marie-Louse Schuttelaar

Journal:

Contact Dermatitis

Year:

2011

Language:

english

File:

PDF, 105 KB

english, 2011

14

Delayed-type hypersensitivity reaction to paraphenylenediamine is mediated by 2 different pathways of antigen recognition by specific αβ+ human T-cell clones

Sonja Sieben, Yo Kawakubo, Tames Al Masaoudi, Hans F. Merk, Brunhilde Blömeke

Journal:

Journal of Allergy and Clinical Immunology

Year:

2002

Language:

english

File:

PDF, 186 KB

english, 2002

15

Evaluation of DNA-binding activity of hydroxyanthraquinones occurring in Rubia tinctorum L

Poginsky, Barbara, Westendorf, Johannes, Blömeke, Brunhilde, Marquardt, Hans, Hewer, Alan, Grover, Philip L., Phillips, David H.

Journal:

Year:

1991

Language:

english

File:

PDF, 5.93 MB

english, 1991

16

Characterization of T Cell Responses to Fragrances

Sonja Sieben, Michael Hertl, Tames Al Masaoudi, Hans F. Merk, Brunhilde Blömeke

Journal:

Toxicology and Applied Pharmacology

Year:

2001

Language:

english

File:

PDF, 170 KB

english, 2001

17

Formation of genotoxic metabolites from anthraquinone glycosides, present in Rubia tinctorum L.

Brunhilde Blömeke, Barbara Poginsky, Christoph Schmutte, Hildegard Marquardt, Johannes Westendorf

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

1992

Language:

english

File:

PDF, 532 KB

english, 1992

18

Metabolism of 1,8-cineole by human cytochrome P450 enzymes: identification of a new hydroxylated metabolite

Mike Duisken, Frank Sandner, Brunhilde Blömeke, Juliane Hollender

Journal:

Biochimica et Biophysica Acta (BBA) - General Subjects

Year:

2005

Language:

english

File:

PDF, 172 KB

english, 2005

19

Evaluation of cytochrome P450 1 (CYP1) and N-acetyltransferase 1 (NAT1) activities in HaCaT cells: Implications for the development of in vitro techniques for predictive testing of contact sensitizers

Jutta Bonifas, Jenny Hennen, Dorothea Dierolf, Michaela Kalmes, Brunhilde Blömeke

Journal:

Toxicology in Vitro

Year:

2010

Language:

english

File:

PDF, 489 KB

english, 2010

20

Potential of coculture in vitro models to study inflammatory and sensitizing effects of particles on the lung

Sebastian G. Klein, Jenny Hennen, Tommaso Serchi, Brunhilde Blömeke, Arno C. Gutleb

Journal:

Toxicology in Vitro

Year:

2011

Language:

english

File:

PDF, 1.41 MB

english, 2011

21

Influence of TNF-a and PPD on N-acetyltransferase 1 in keratinocytes and monocytes

Jutta Bonifas, Jutta Bonifas, Simone Scheitza, Brunhilde Blömeke

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 86 KB

english, 2012

22

Impact of N-acetyltransferase 1 on sensitizing potential of para-phenylenediamine

Simone Scheitza, Jenny Hennen, Dorothea Dierolf, Brunhilde Blömeke

Journal:

Toxicology Letters

Year:

2012

Language:

english

File:

PDF, 97 KB

english, 2012

23

Rapid and reliable genotyping for the Toll-like receptor 4 A896G polymorphism using fluorescence-labeled hybridization probes in a real-time polymerase chain reaction assay

Michael Heesen, Martina Wessiepe, Dagmar Kunz, Katarina Vasickova, Brunhilde Blomeke

Journal:

Clinica Chimica Acta

Year:

2003

Language:

english

File:

PDF, 115 KB

english, 2003

24

Quantitative risk assessment for skin sensitisation: Consideration of a simplified approach for hair dye ingredients

Goebel, Carsten, Diepgen, Thomas L., Krasteva, Maya, Schlatter, Harald, Nicolas, Jean-Francois, Blömeke, Brunhilde, Coenraads, Pieter Jan, Schnuch, Axel, Taylor, James S., Pungier, Jacquemine, Fautz,

Journal:

Regulatory Toxicology and Pharmacology

Year:

2012

Language:

english

File:

PDF, 264 KB

english, 2012

25

Characterisation of dendritic cell responses to para-phenylenediamine

Angela Heckelen, Liane Wilbers, Brunhilde Blomeke

Journal:

Toxicology Letters

Year:

2007

Language:

english

File:

PDF, 88 KB

english, 2007

26

Functionality of CD4+CD25+ regulatory T cells in subjects with allergic contact dermatitis to para-phenylenediamine

Silke Grannemann, Pieter-Jan Coenraads, Liane Wilbers, Brunhilde Blömeke

Journal:

Toxicology Letters

Year:

2008

Language:

english

File:

PDF, 94 KB

english, 2008

27

Expression of major Phase 1 and 2 enzymes in HaCaT cells

Jutta Lichter, Jennifer Hennen, Dierolf Dorothea, Kalmes Michaela, Moeller Ruth, Breuer Sebastian, Brunhilde Blömeke

Journal:

Toxicology Letters

Year:

2008

Language:

english

File:

PDF, 88 KB

english, 2008

28

Impact of eugenol and isoeugenol on the AhR translocation and its target genes in human immortalized keratinocytes (HaCaT)

Michaela Kalmes, Jennifer Hennen, Brunhilde Blömeke

Journal:

Toxicology Letters

Year:

2008

Language:

english

File:

PDF, 89 KB

english, 2008

29

N-Acetyltransferase 1 (NAT1) and cytochrome P450 1 (CYP1) activities in subtypes of HaCaT cells

Jutta Bonifas, Jenny Hennen, Simone Scheitza, Brunhilde Blömeke

Journal:

Toxicology Letters

Year:

2009

Language:

english

File:

PDF, 79 KB

english, 2009

30

p-phenylenediamine (PPD) N-acetylation in human skin cytosol

Kawakubo, Yo, Blömeke, Brunhilde, Merk, Hans

Journal:

Journal of Dermatological Science

Year:

1998

Language:

english

File:

PDF, 179 KB

english, 1998

31

Cyanamide-mediated Inhibition of N-acetyltransferase 1

Dierolf, Dorothea, Scheitza, Simone, Bonifas, Jutta, Blömeke, Brunhilde

Journal:

Year:

2012

Language:

english

File:

PDF, 1.02 MB

english, 2012

32

Verbesserte Aktivierung und Detektion von Prohaptenen in einer Ko-Kultur

Jennifer Hennen, Brunhilde Blömeke

Journal:

Year:

2013

Language:

german

File:

PDF, 432 KB

german, 2013

33

Variable NAT1 Enzyme Activity in Long-Term Cultured Human HaCaT Keratinocytes

Scheitza, Simone, Bonifas, Jutta, Blömeke, Brunhilde

Journal:

Journal of Toxicology and Environmental Health

Year:

2012

Language:

english

File:

PDF, 260 KB

english, 2012

34

An improved 3D tetraculture system mimicking the cellular organisation at the alveolar barrier to study the potential toxic effects of particles on the lung

Klein, Sebastian G, Serchi, Tommaso, Hoffmann, Lucien, Blömeke, Brunhilde, Gutleb, Arno C

Journal:

Particle and Fibre Toxicology

Year:

2013

Language:

english

File:

PDF, 8.03 MB

english, 2013

35

The optimal patch test concentration for ascaridole as a sensitizing component of tea tree oil

Christoffers, Wietske Andrea, Blömeke, Brunhilde, Coenraads, Pieter-Jan, Schuttelaar, Marie-Louise Anna

Journal:

Contact Dermatitis

Year:

2014

Language:

english

File:

PDF, 639 KB

english, 2014

36

Introduction of a methoxymethyl side chain into p-phenylenediamine attenuates its sensitizing potency and reduces the risk of allergy induction

Goebel, Carsten, Troutman, John, Hennen, Jenny, Rothe, Helga, Schlatter, Harald, Gerberick, G. Frank, Blömeke, Brunhilde

Journal:

Toxicology and Applied Pharmacology

Year:

2014

Language:

english

File:

PDF, 691 KB

english, 2014

37

Quantitative risk assessment for skin sensitization: A simplified approach for hair dye ingredients?

Goebel, Carsten, Diepgen, Thomas, Krasteva, Maya, Schlatter, Harald, Nicolas, Jean-Francois, Blömeke, Brunhilde, Coenraads, Pieter Jan, Schnuch, Axel, Taylor, James S., Pungier, Jacquemine, Fautz, Rol

Journal:

Toxicology Letters

Year:

2013

Language:

english

File:

PDF, 54 KB

english, 2013

38

N -Acetyltransferase 1 in Colon and Rectal Cancer Cases from an Industrialized Area

Roemer, Hermann C., Weistenhöfer, Wobbeke, Löhlein, Dietrich, Geller, Frank, Blömeke, Brunhilde, Golka, Klaus

Journal:

Journal of Toxicology and Environmental Health

Year:

2008

Language:

english

File:

PDF, 73 KB

english, 2008

39

Arylalkylamine N-Acetyltransferase ( AANAT ) Genotype as a Personal Trait in Melatonin Synthesis

Blömeke, Brunhilde, Golka, Klaus, Griefahn, Barbara, Roemer, Hermann C.

Journal:

Journal of Toxicology and Environmental Health

Year:

2008

Language:

english

File:

PDF, 106 KB

english, 2008

40

Induction of skin sensitization and quantitative risk assessment considerations for hair dyes

Goebel, Carsten, Troutman, John, Hennen, Jennifer, Rothe, Helga, Schlatter, Harald, Gerberick, G. Frank, Blömeke, Brunhilde

Journal:

Toxicology Letters

Year:

2014

Language:

english

File:

PDF, 56 KB

english, 2014

41

Elicitation of the immune response to hair dye contact allergens in humans

Bijkersma-Pot, Laura, Blomeke, Brunhilde, Goebel, Carsten, Coenraads, Pieter Jan, Diepgen, Thomas

Journal:

Toxicology Letters

Year:

2014

Language:

english

File:

PDF, 56 KB

english, 2014

42

An in vitro coculture approach to assess the impact of skin keratinocytes on chemical-induced activation of dendritic cells

Hennen, Jennifer, Kinitz, Tim, Blömeke, Brunhilde

Journal:

Toxicology Letters

Year:

2014

Language:

english

File:

PDF, 67 KB

english, 2014

43

Activation and deactivation of aromatic amine hair dyes in the skin

Blömeke, Brunhilde

Journal:

Toxicology Letters

Year:

2014

Language:

english

File:

PDF, 53 KB

english, 2014

44

Impact of Eugenol and Isoeugenol on AhR Translocation, Target Gene Expression, and Proliferation in Human HaCaT Keratinocytes

Kalmes, Michaela, Blömeke, Brunhilde

Journal:

Journal of Toxicology and Environmental Health

Year:

2012

Language:

english

File:

PDF, 646 KB

english, 2012

45

Extrahepatic metabolism at the body's internal–external interfaces

Gundert-Remy, Ursula, Bernauer, Ulrike, Blömeke, Brunhilde, Döring, Barbara, Fabian, Eric, Goebel, Carsten, Hessel, Stefanie, Jäckh, Christine, Lampen, Alfonso, Oesch, Franz, Petzinger, Ernst, Völkel,

Journal:

Drug Metabolism Reviews

Year:

2014

Language:

english

File:

PDF, 1.43 MB

english, 2014

46

Co-sensitization to ascaridole and tea tree oil

Christoffers, Wietske Andrea, Blömeke, Brunhilde, Coenraads, Pieter-Jan, Schuttelaar, Marie-Louise Anna

Journal:

Contact Dermatitis

Year:

2013

Language:

english

File:

PDF, 527 KB

english, 2013

47

Expression of N -Acetyltransferase in Monocyte-Derived Dendritic Cells∗

Lichter, Jutta, Heckelen, Angela, Fischer, Klaus, Blömeke, Brunhilde

Journal:

Journal of Toxicology and Environmental Health

Year:

2008

Language:

english

File:

PDF, 145 KB

english, 2008

48

Sequence Variations in Subjects with Self-Reported Multiple Chemical Sensitivity (sMCS): A Case-Control Study

Wiesmüller, Gerhard A., Niggemann, Hiltrud, Weißbach, Wibke, Riley, Felix, Maarouf, Zackaria, Dott, Wolfgang, Kunert, Hanns-Jürgen, Zerres, Klaus, Eggermann, Thomas, Blömeke, Brunhilde

Journal:

Journal of Toxicology and Environmental Health

Year:

2008

Language:

english

File:

PDF, 104 KB

english, 2008

49

Impact of aryl hydrocarbon receptor (AhR) knockdown on cell cycle progression in human HaCaT keratinocytes

Kalmes, Michaela, Hennen, Jenny, Clemens, Judith, Blömeke, Brunhilde

Journal:

Biological Chemistry

Year:

2011

Language:

english

File:

PDF, 372 KB

english, 2011

50

Sensitization Assays: Monocyte-Derived Dendritic Cells Versus a Monocytic Cell Line (THP-1)

Tietze, Corinna, Blömeke, Brunhilde

Journal:

Journal of Toxicology and Environmental Health

Year:

2008

Language:

english

File:

PDF, 165 KB

english, 2008